Apoaequorin (Prevagen) to Improve Memory
Apoaequorin (Prevagen) to Improve Memory
November 1, 2021 (Issue: 1636)
A synthetic form of the protein apoaequorin is the
active ingredient in the over-the-counter dietary
supplement Prevagen (Quincy Bioscience), which
is heavily marketed to improve memory.
- GA Morrill et al. Computational comparison of a calcium-dependent jellyfish protein (apoaequorin) and calmodulin-cholesterol in short-term memory maintenance. Neurosci Lett 2017; 642:113.
- Alzheimer's Association Calcium Hypothesis Workgroup. Calcium hypothesis of Alzheimer's disease and brain aging: a framework for integrating new evidence into a comprehensive theory of pathogenesis. Alzheimers Dement 2017; 13:178.
- DL Moran et al. Safety assessment of the calcium-binding protein, apoaequorin, expressed by Escherichia coli. Regul Toxicol Pharmacol 2014; 69:243.
- DL Moran et al. Effects of a supplement containing apoaequorin on verbal learning in older adults in the community. Adv Mind Body Med 2016; 30:4.
- KC Lerner. Madison Memory Study: a randomized, double-blinded, placebo-controlled trial of apoaequorin in community-dwelling, older adults. Clinical Trial Synopsis QB-0011. Quincy Bioscience, LLC. August 1, 2016. Available at: https://bit.ly/3mL1634. Accessed October 14, 2021.
- FDA ICECI Warning Letter. Quincy Bioscience Manufacturing Inc. October 16, 2012. Available at: https://bit.ly/3jn8vUu. Accessed October 14, 2021.
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