The Medical Letter on Drugs and Therapeutics
FROM
ISSUE1746
ISSUE1746
January 19, 2026
Donidalorsen (Dawnzera) for Prevention of Hereditary Angioedema Attacks
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Donidalorsen (Dawnzera) for Prevention of Hereditary Angioedema Attacks
January 19, 2026 (Issue: 1746)
Donidalorsen (Dawnzera – Ionis), a subcutaneously
injected prekallikrein-directed antisense oligonucleotide,
has been approved by the FDA for prevention
of hereditary angioedema (HAE) attacks in patients
≥12 years old. It is the first...more
The Medical Letter is a subscriber-funded nonprofit organization that publishes critical appraisals of new prescription drugs and comparative reviews of drugs for common diseases.
