Matching articles for "Diastat"
In Brief: New Benzodiazepine Warnings
The Medical Letter on Drugs and Therapeutics • November 2, 2020; (Issue 1610)
The FDA now requires boxed warnings in the package
inserts of benzodiazepines describing the potential for
these drugs to be abused and misused and to cause
addiction and physical dependence....
The FDA now requires boxed warnings in the package
inserts of benzodiazepines describing the potential for
these drugs to be abused and misused and to cause
addiction and physical dependence. Benzodiazepine
labels have contained a boxed warning about a risk of
serious drug interactions with opioids since 2016.
Intranasal Diazepam (Valtoco) and Midazolam (Nayzilam) for Seizure Clusters
The Medical Letter on Drugs and Therapeutics • April 20, 2020; (Issue 1596)
The FDA has approved nasal spray formulations of
the benzodiazepines diazepam (Valtoco — Neurelis)
and midazolam (Nayzilam — UCB) for acute treatment
of intermittent episodes of frequent seizure...
The FDA has approved nasal spray formulations of
the benzodiazepines diazepam (Valtoco — Neurelis)
and midazolam (Nayzilam — UCB) for acute treatment
of intermittent episodes of frequent seizure activity
(seizure clusters). Diazepam rectal gel (Diastat, Diastat
AcuDial, and generics) has been used for this indication
for many years.
Drugs for Epilepsy
The Medical Letter on Drugs and Therapeutics • July 31, 2017; (Issue 1526)
Treatment of epilepsy should begin with a single
antiepileptic drug (AED), increasing its dosage
gradually until seizures are controlled or adverse
effects become intolerable. If seizures...
Treatment of epilepsy should begin with a single
antiepileptic drug (AED), increasing its dosage
gradually until seizures are controlled or adverse
effects become intolerable. If seizures persist,
specialists generally recommend trying at least
one and sometimes a second alternative drug as
monotherapy before considering use of two drugs
concurrently. When used for the appropriate seizure
type, AEDs are roughly equivalent in efficacy. Drug
choice is usually based on factors such as ease of
use, adverse effects, drug interactions, presence of
comorbidities, and cost.
Drugs for Epilepsy
The Medical Letter on Drugs and Therapeutics • May 1, 2003; (Issue 9)
Treatment of epilepsy should begin with a single drug, increasing the dosage gradually until seizures are controlled or adverse effects become unacceptable. If seizures continue and further dosage increases...
Treatment of epilepsy should begin with a single drug, increasing the dosage gradually until seizures are controlled or adverse effects become unacceptable. If seizures continue and further dosage increases appear inadvisable because of adverse effects, most Medical Letter consultants generally prescribe at least one and sometimes a second alternative drug as monotherapy before considering use of two drugs at the same time. Most antiepileptic drugs initially approved by the FDA only for adjunctive therapy are probably also effective as monotherapy. Many of the drugs used to treat epilepsy interact with each other (see table beginning on page 63) and with other drugs; for interactions with other drugs, see The Medical Letter Handbook of Adverse Drug Interactions, 2003. The treatment of status epilepticus is not included here.