Matching articles for "ivermectin"
Lotilaner (Xdemvy) for Demodex Blepharitis
The Medical Letter on Drugs and Therapeutics • June 24, 2024; (Issue 1705)
The FDA has approved a 0.25% ophthalmic solution
of the ectoparasiticide lotilaner (Xdemvy – Tarsus) for
treatment of Demodex blepharitis. Lotilaner is the first
drug to be approved in the US for this...
The FDA has approved a 0.25% ophthalmic solution
of the ectoparasiticide lotilaner (Xdemvy – Tarsus) for
treatment of Demodex blepharitis. Lotilaner is the first
drug to be approved in the US for this indication.
Drugs for Head Lice
The Medical Letter on Drugs and Therapeutics • June 10, 2024; (Issue 1704)
Pediculosis capitis (head lice infestations) occur in
all age groups, but especially in elementary school
children. In most cases, transmission occurs by
head-to-head contact. Pharmacologic treatment...
Pediculosis capitis (head lice infestations) occur in
all age groups, but especially in elementary school
children. In most cases, transmission occurs by
head-to-head contact. Pharmacologic treatment is
recommended for persons with live lice or eggs (nits)
within 1 cm of the scalp. Topical pediculicides should
be tried first. Oral therapy is occasionally required for
refractory infestations.
Drugs for Rosacea
The Medical Letter on Drugs and Therapeutics • February 5, 2024; (Issue 1695)
Rosacea is a common, chronic inflammatory facial
eruption of unknown cause. It is more prevalent
in women than in men, and disease onset typically
occurs after age 30. Rosacea is characterized
by erythema,...
Rosacea is a common, chronic inflammatory facial
eruption of unknown cause. It is more prevalent
in women than in men, and disease onset typically
occurs after age 30. Rosacea is characterized
by erythema, telangiectasia, and flushing, and
sometimes by recurrent, progressive crops of
acneiform papules and pustules, usually on the
central part of the face. Some patients develop
granulomas and tissue hypertrophy, which may lead
to rhinophyma (a bulbous nose), particularly in men.
Blepharitis and conjunctivitis are common. Keratitis
and corneal scarring occur rarely.
Comparison Table: Some Topical Drugs for Rosacea (online only)
The Medical Letter on Drugs and Therapeutics • February 5, 2024; (Issue 1695)
...
View the Comparison Table: Some Topical Drugs for Rosacea
In Brief: OTC Ivermectin for Head Lice
The Medical Letter on Drugs and Therapeutics • June 26, 2023; (Issue 1679)
Topical ivermectin lotion 0.5% (Sklice, and generics),
which has been available by prescription since 2012,
is now FDA-approved for sale over the counter (OTC)
for treatment of head lice in patients ≥6...
Topical ivermectin lotion 0.5% (Sklice, and generics),
which has been available by prescription since 2012,
is now FDA-approved for sale over the counter (OTC)
for treatment of head lice in patients ≥6 months old.
Ivermectin is also available by prescription as a 1%
cream (Soolantra) approved for topical treatment of
inflammatory lesions of rosacea and in oral tablets
(Stromectol, and generics) for treatment of various
parasitic infections.
COVID-19 Update: Metformin to Prevent Long Covid?
The Medical Letter on Drugs and Therapeutics • May 29, 2023; (Issue 1677)
Results from a double-blind trial suggest that off-label
use of the oral antihyperglycemic drug metformin
in patients with COVID-19 may decrease the risk
of post-acute sequelae of SARS-CoV-2...
Results from a double-blind trial suggest that off-label
use of the oral antihyperglycemic drug metformin
in patients with COVID-19 may decrease the risk
of post-acute sequelae of SARS-CoV-2 infection
("long COVID").
Epsolay - A Benzoyl Peroxide Cream for Rosacea
The Medical Letter on Drugs and Therapeutics • February 6, 2023; (Issue 1669)
Epsolay (Galderma), a 5% benzoyl peroxide cream,
has been approved by the FDA for treatment of
inflammatory lesions of rosacea in adults. It is the first
product containing benzoyl peroxide to be...
Epsolay (Galderma), a 5% benzoyl peroxide cream,
has been approved by the FDA for treatment of
inflammatory lesions of rosacea in adults. It is the first
product containing benzoyl peroxide to be approved
in the US for treatment of rosacea. Benzoyl peroxide
formulations approved for acne have been used off-label
to treat rosacea for years, but itching and burning
have limited their use.
Drugs for Sexually Transmitted Infections
The Medical Letter on Drugs and Therapeutics • June 27, 2022; (Issue 1653)
This article includes recommendations for management
of most sexually transmitted infections (STIs)
other than HIV and viral hepatitis. Some of the
indications and dosages recommended here have
not been...
This article includes recommendations for management
of most sexually transmitted infections (STIs)
other than HIV and viral hepatitis. Some of the
indications and dosages recommended here have
not been approved by the FDA (see Table 1).
COVID-19 Update: NIH Recommends Against Ivermectin
The Medical Letter on Drugs and Therapeutics • June 13, 2022; (Issue 1652)
On April 29, the NIH recommended against use of the antiparasitic drug ivermectin for treatment of COVID-19 outside of a clinical trial. The recommendation was made because recent randomized, placebo-controlled...
On April 29, the NIH recommended against use of the antiparasitic drug ivermectin for treatment of COVID-19 outside of a clinical trial. The recommendation was made because recent randomized, placebo-controlled trials of ivermectin have produced negative results and because alternative drugs that have been shown to be effective for treatment of COVID-19 are available.
Minocycline Foam (Zilxi) for Rosacea
The Medical Letter on Drugs and Therapeutics • November 16, 2020; (Issue 1611)
The FDA has approved a 1.5% topical foam formulation
of minocycline (Zilxi – Foamix) for treatment of
inflammatory lesions of rosacea in adults. It is
the only topical minocycline product approved...
The FDA has approved a 1.5% topical foam formulation
of minocycline (Zilxi – Foamix) for treatment of
inflammatory lesions of rosacea in adults. It is
the only topical minocycline product approved for
this indication. The same manufacturer markets
minocycline foam 4% (Amzeeq) for treatment of acne
in patients ≥9 years old.
Table: Treatments Considered for COVID-19 (Archived) (online only)
The Medical Letter on Drugs and Therapeutics • April 6, 2020; (Issue 1595)
...
View the Table: Treatments Considered for COVID-19
Drugs for Sexually Transmitted Infections
The Medical Letter on Drugs and Therapeutics • July 3, 2017; (Issue 1524)
The text and tables that follow include recommendations
for management of sexually transmitted
infections (STIs) other than HIV and viral hepatitis.
Some of the indications and dosages recommended
here have...
The text and tables that follow include recommendations
for management of sexually transmitted
infections (STIs) other than HIV and viral hepatitis.
Some of the indications and dosages recommended
here have not been approved by the FDA.
Oxymetazoline Cream (Rhofade) for Rosacea
The Medical Letter on Drugs and Therapeutics • May 22, 2017; (Issue 1521)
The FDA has approved the selective alpha1A-adrenergic
receptor agonist oxymetazoline as a 1% cream (Rhofade
– Allergan) for topical treatment of persistent facial
erythema of rosacea in adults....
The FDA has approved the selective alpha1A-adrenergic
receptor agonist oxymetazoline as a 1% cream (Rhofade
– Allergan) for topical treatment of persistent facial
erythema of rosacea in adults. Brimonidine, a selective
alpha2-adrenergic receptor agonist, was approved in
2013 as a 0.33% gel (Mirvaso) for the same indication.
Like Mirvaso, Rhofade is not indicated for treatment of
inflammatory lesions of rosacea. Oxymetazoline has
been available over the counter for many years as a
nasal decongestant spray (Afrin, and others).
Comparison Table: Some Topical Drugs for Rosacea (online only)
The Medical Letter on Drugs and Therapeutics • May 22, 2017; (Issue 1521)
...
View the Comparison Table: Some Topical Drugs for Rosacea
Drugs for Head Lice
The Medical Letter on Drugs and Therapeutics • November 21, 2016; (Issue 1508)
Head lice infestation occurs in all age groups, but especially
in elementary school children. In most cases,
transmission occurs by head-to-head...
Head lice infestation occurs in all age groups, but especially
in elementary school children. In most cases,
transmission occurs by head-to-head contact.
Drugs for Rosacea
The Medical Letter on Drugs and Therapeutics • February 1, 2016; (Issue 1487)
This common, chronic inflammatory facial eruption
of unknown cause is more prevalent in women
than in men. Rosacea is characterized by erythema
and telangiectasia, and sometimes by recurrent,
progressive...
This common, chronic inflammatory facial eruption
of unknown cause is more prevalent in women
than in men. Rosacea is characterized by erythema
and telangiectasia, and sometimes by recurrent,
progressive crops of acneiform papules and pustules,
usually on the central part of the face. Some patients
develop granulomas and tissue hypertrophy, which
may lead to rhinophyma (a bulbous nose), particularly
in men. Blepharitis and conjunctivitis are common.
Keratitis and corneal scarring occur rarely.
Ivermectin Cream (Soolantra) for Rosacea
The Medical Letter on Drugs and Therapeutics • April 13, 2015; (Issue 1466)
The FDA has approved a 1% cream formulation
of the antiparasitic drug ivermectin (Soolantra –
Galderma) for topical treatment of inflammatory
lesions of rosacea. Ivermectin is available in the US
in...
The FDA has approved a 1% cream formulation
of the antiparasitic drug ivermectin (Soolantra –
Galderma) for topical treatment of inflammatory
lesions of rosacea. Ivermectin is available in the US
in tablets (Stromectol, and generics) for treatment of
onchocerciasis and other worm infestations and as a
0.5% lotion (Sklice) for treatment of head lice.
Drugs for Sexually Transmitted Infections
The Medical Letter on Drugs and Therapeutics • September 1, 2013; (Issue 133)
Many infections can be transmitted during sexual contact.
The text and tables that follow include recommendations
for management of sexually transmitted
infections (STIs) other than HIV, viral hepatitis,...
Many infections can be transmitted during sexual contact.
The text and tables that follow include recommendations
for management of sexually transmitted
infections (STIs) other than HIV, viral hepatitis, and
enteric infections. Some of the indications and
dosages recommended here have not been approved
by the FDA.
Ivermectin (Sklice) Topical Lotion for Head Lice
The Medical Letter on Drugs and Therapeutics • August 6, 2012; (Issue 1396)
The FDA has approved the antiparasitic drug ivermectin
in a 0.5% lotion (Sklice – Sanofi Pasteur) as a
single-use topical treatment for head lice in patients ≥6
months old. Oral ivermectin (Stromectol...
The FDA has approved the antiparasitic drug ivermectin
in a 0.5% lotion (Sklice – Sanofi Pasteur) as a
single-use topical treatment for head lice in patients ≥6
months old. Oral ivermectin (Stromectol – Merck) is
effective for treatment of head lice resistant to other
therapies, but it has not been approved by the FDA for
this indication.
Spinosad (Natroba) Topical Suspension for Head Lice
The Medical Letter on Drugs and Therapeutics • June 27, 2011; (Issue 1367)
The FDA has approved spinosad 0.9% suspension (Natroba – ParaPro) for topical treatment of head lice infestation in patients ≥4 years old. It is available only by...
The FDA has approved spinosad 0.9% suspension (Natroba – ParaPro) for topical treatment of head lice infestation in patients ≥4 years old. It is available only by prescription.
Drugs for Sexually Transmitted Infections
The Medical Letter on Drugs and Therapeutics • July 1, 2010; (Issue 95)
Many infections can be transmitted during sexual contact. The text and tables that follow are limited to management of sexually transmitted infections (STIs) other than HIV, viral hepatitis and enteric...
Many infections can be transmitted during sexual contact. The text and tables that follow are limited to management of sexually transmitted infections (STIs) other than HIV, viral hepatitis and enteric infections. The drugs of choice, their dosages and alternatives are listed in a table that begins on page 54. A table listing the adverse effects of some of these antimicrobials begins on page 58.
Benzyl Alcohol Lotion for Head Lice
The Medical Letter on Drugs and Therapeutics • July 27, 2009; (Issue 1317)
The FDA has approved benzyl alcohol lotion, 5% (Ulesfia Lotion - Sciele) for treatment of head lice in patients ≥6 months old. The active ingredient is 5% benzyl alcohol; the vehicle is 5% mineral...
The FDA has approved benzyl alcohol lotion, 5% (Ulesfia Lotion - Sciele) for treatment of head lice in patients ≥6 months old. The active ingredient is 5% benzyl alcohol; the vehicle is 5% mineral oil.
Drugs for Sexually Transmitted Infections
The Medical Letter on Drugs and Therapeutics • September 1, 2007; (Issue 61)
Many infections can be transmitted during sexual contact. The text and tables that follow are limited to management of sexually transmitted infections (STIs) other than HIV, viral hepatitis and enteric...
Many infections can be transmitted during sexual contact. The text and tables that follow are limited to management of sexually transmitted infections (STIs) other than HIV, viral hepatitis and enteric infections. Guidelines are available from the US Centers for Disease Control and Prevention (CDC) with detailed recommendations for treatment of these diseases.
Drugs for Head Lice
The Medical Letter on Drugs and Therapeutics • August 15, 2005; (Issue 1215)
Head lice occur in all age groups, but especially in elementary school children during the winter months. Infestations are becoming more difficult to treat because of increasing resistance to the chemical...
Head lice occur in all age groups, but especially in elementary school children during the winter months. Infestations are becoming more difficult to treat because of increasing resistance to the chemical pediculicides commonly used, particularly those that are available over-the-counter (OTC).
Drugs for Sexually Transmitted Infections
The Medical Letter on Drugs and Therapeutics • October 1, 2004; (Issue 26)
Many infections can be transmitted during sexual contact. The text and tables that follow are limited to management of sexually transmitted infections (STIs) other than HIV, viral hepatitis and enteric...
Many infections can be transmitted during sexual contact. The text and tables that follow are limited to management of sexually transmitted infections (STIs) other than HIV, viral hepatitis and enteric infections. Guidelines are available from the US Centers for Disease Control and Prevention (CDC) with detailed recommendations for treatment of these diseases (MMWR Recomm Rep 2002; 51, RR-6:1). New guidelines are expected soon.
Drugs for Parasitic Infections
The Medical Letter on Drugs and Therapeutics • August 16, 2004; (Issue 1189)
Parasitic infections are found throughout the world. With increasing travel, immigration, use of immunosuppressive drugs and the spread of AIDS, physicians anywhere may see infections caused by previously...
Parasitic infections are found throughout the world. With increasing travel, immigration, use of immunosuppressive drugs and the spread of AIDS, physicians anywhere may see infections caused by previously unfamiliar parasites. The table below lists first-choice and alternative drugs for most parasitic infections. The brand names and manufacturers of the drugs are listed in this article.
Drug Interactions
The Medical Letter on Drugs and Therapeutics • June 8, 2003; (Issue 1158)
Changes caused by one drug in the absorption, distribution, metabolism or excretion of another may lead to a pharmacokinetic adverse drug interaction (DN Juurlink et al, JAMA 2003; 289:1652). Additive drug...
Changes caused by one drug in the absorption, distribution, metabolism or excretion of another may lead to a pharmacokinetic adverse drug interaction (DN Juurlink et al, JAMA 2003; 289:1652). Additive drug interactions, such as vasodilation caused by both sildenafil (Viagra) and nitrates, can also have adverse effects.
Drugs for Parasitic Infections
The Medical Letter on Drugs and Therapeutics • April 1, 2002; (Issue 1127)
Superseded--purchase updated Parasitic Infections articleParasitic infections are found throughout the world. With increasing travel, immigration, use of immunosuppressive drugs and the spread of AIDS,...
Superseded--purchase updated Parasitic Infections article
Parasitic infections are found throughout the world. With increasing travel, immigration, use of immunosuppressive drugs and the spread of AIDS, physicians anywhere may see infections caused by previously unfamiliar parasites.
Note: Drugs for Parasitic Infections, revised and updated, is now available to both subscribers and nonsubscribers on our web site. This article, a bi-annual feature of The Medical Letter for many years, will not be published as a printed issue in 2002, but is included in the 16th edition of The Medical Letter Handbook of Antimicrobial Therapy. The handbook is now available and can be ordered by calling customer service at 1-800-211-2769.
Parasitic infections are found throughout the world. With increasing travel, immigration, use of immunosuppressive drugs and the spread of AIDS, physicians anywhere may see infections caused by previously unfamiliar parasites.
Note: Drugs for Parasitic Infections, revised and updated, is now available to both subscribers and nonsubscribers on our web site. This article, a bi-annual feature of The Medical Letter for many years, will not be published as a printed issue in 2002, but is included in the 16th edition of The Medical Letter Handbook of Antimicrobial Therapy. The handbook is now available and can be ordered by calling customer service at 1-800-211-2769.
Drugs for Sexually Transmitted Infections
The Medical Letter on Drugs and Therapeutics • September 24, 1999; (Issue 1062)
Many infections can be transmitted during sexual contact. The text and tables [in this article] are limited to treatment of non-HIV infections associated primarily with sexual...
Many infections can be transmitted during sexual contact. The text and tables [in this article] are limited to treatment of non-HIV infections associated primarily with sexual transmission.
Malathion for the Treatment of Head Lice
The Medical Letter on Drugs and Therapeutics • August 13, 1999; (Issue 1059)
...
0.5% malathion in 78% isopropanol was recently approved by the FDA for treatment of head lice.
Drugs for Parasitic Infections
The Medical Letter on Drugs and Therapeutics • January 2, 1998; (Issue 1017)
(Superseded by the 2013 version. Click here to purchase.)Parasitic infections are found throughout the world. With increasing travel, immigration, use of immunosuppressive drugs and the spread of AIDS,...
(Superseded by the 2013 version. Click here to purchase.)
Parasitic infections are found throughout the world. With increasing travel, immigration, use of immunosuppressive drugs and the spread of AIDS, physicians anywhere may see infections caused by previously unfamiliar parasites. The table lists first-choice and alternative drugs for most parasitic infections.
Parasitic infections are found throughout the world. With increasing travel, immigration, use of immunosuppressive drugs and the spread of AIDS, physicians anywhere may see infections caused by previously unfamiliar parasites. The table lists first-choice and alternative drugs for most parasitic infections.
Drugs for Head Lice
The Medical Letter on Drugs and Therapeutics • January 19, 1997; (Issue 992)
Several readers have asked the Medical Letter to review the treatment of head lice, which apparently have become increasingly resistant to recommended drugs (KY Mumcuoglu, American Entomologist, Fall 1996,...
Several readers have asked the Medical Letter to review the treatment of head lice, which apparently have become increasingly resistant to recommended drugs (KY Mumcuoglu, American Entomologist, Fall 1996, page 175). Assays for drug resistance of head lice have not been standardized, however, and poor technique, such as not using a louse comb after treatment to remove lice and nits (eggs), may be responsible for some treatment failures. The last Medical Letter article on treatment of parasitic infections (vol. 37, page 99, November 10, 1995) recommended 1% permethrin (Nix) or 0.5% malathion (Prioderm; Ovide) as the drug of choice for treatment of head lice and pyrethrins with piperonyl butoxide (Rid, and others) as an alternative.