Matching articles for "iron"
Daprodustat (Jesduvroq) for Anemia of Chronic Kidney Disease
The Medical Letter on Drugs and Therapeutics • February 19, 2024; (Issue 1696)
The FDA has approved daprodustat (Jesduvroq –
GSK), a hypoxia-inducible factor prolyl hydroxylase
inhibitor (HIF-PHI), for oral treatment of anemia due
to chronic kidney disease (CKD) in adults who...
The FDA has approved daprodustat (Jesduvroq –
GSK), a hypoxia-inducible factor prolyl hydroxylase
inhibitor (HIF-PHI), for oral treatment of anemia due
to chronic kidney disease (CKD) in adults who have
been on dialysis for at least 4 months. It is the first
HIF-PHI and the first oral drug to be approved in the
US for this indication.
IV Ferric Carboxymaltose (Injectafer) for Iron Deficiency in Heart Failure
The Medical Letter on Drugs and Therapeutics • February 5, 2024; (Issue 1695)
Ferric carboxymaltose (Injectafer – American
Regent) is now FDA-approved for IV treatment of iron
deficiency in adults with New York Heart Association
(NYHA) class II/III heart failure to improve...
Ferric carboxymaltose (Injectafer – American
Regent) is now FDA-approved for IV treatment of iron
deficiency in adults with New York Heart Association
(NYHA) class II/III heart failure to improve exercise
capacity. Iron deficiency is present in approximately
30% of patients with heart failure; it has been
associated with reduced quality of life and increased
hospitalization and mortality. Injectafer is the first
IV iron preparation to be approved for this indication.
It was previously approved for treatment of iron
deficiency anemia in children and adults.
Triferic for Iron Replacement
The Medical Letter on Drugs and Therapeutics • March 27, 2017; (Issue 1517)
The FDA has approved ferric pyrophosphate
citrate solution (Triferic – Rockwell Medical) to
maintain hemoglobin concentrations in adults with
hemodialysis-dependent chronic kidney disease.
Triferic is the...
The FDA has approved ferric pyrophosphate
citrate solution (Triferic – Rockwell Medical) to
maintain hemoglobin concentrations in adults with
hemodialysis-dependent chronic kidney disease.
Triferic is the first iron replacement product that is
added into the hemodialysis solution at each dialysis
procedure.
Drugs for Hypothyroidism
The Medical Letter on Drugs and Therapeutics • October 26, 2015; (Issue 1480)
Primary hypothyroidism is usually the result of
Hashimoto's thyroiditis, thyroidectomy, or radioactive
iodine therapy. Treatment of hypothyroidism with
replacement doses of thyroid hormone is...
Primary hypothyroidism is usually the result of
Hashimoto's thyroiditis, thyroidectomy, or radioactive
iodine therapy. Treatment of hypothyroidism with
replacement doses of thyroid hormone is usually
lifelong. Levothyroxine is the drug of choice.
Ferric Carboxymaltose (Injectafer) for Iron Deficiency Anemia
The Medical Letter on Drugs and Therapeutics • December 9, 2013; (Issue 1431)
The FDA has approved ferric carboxymaltose
(Injectafer – American Regent), a 2-dose intravenous
iron replacement product, for treatment of iron deficiency
anemia (IDA) in adults who cannot tolerate...
The FDA has approved ferric carboxymaltose
(Injectafer – American Regent), a 2-dose intravenous
iron replacement product, for treatment of iron deficiency
anemia (IDA) in adults who cannot tolerate or
have had an unsatisfactory response to oral iron and
in those who have non-dialysis-dependent chronic
kidney disease (CKD). It is the sixth IV iron product
approved in the US.
Correction: Ferumoxytol (Feraheme)
The Medical Letter on Drugs and Therapeutics • April 19, 2010; (Issue 1336)
In the Medical Letter article on Ferumoxytol (Feraheme) - A New Parenteral Iron Formulation (2010; 52:23), the last sentence of the Dosage, Administration and Cost paragraph should have listed the cost of 1...
In the Medical Letter article on Ferumoxytol (Feraheme) - A New Parenteral Iron Formulation (2010; 52:23), the last sentence of the Dosage, Administration and Cost paragraph should have listed the cost of 1 gram of sodium ferric gluconate (Ferrlecit) as about $600.
Ferumoxytol (Feraheme) - A New Parenteral Iron Formulation
The Medical Letter on Drugs and Therapeutics • March 22, 2010; (Issue 1334)
Ferumoxytol (Fer yoo mox’ i tole; Feraheme – AMAG), an intravenous (IV) iron replacement product, has been approved by the FDA for treatment of iron deficiency anemia in adults with chronic kidney disease....
Ferumoxytol (Fer yoo mox’ i tole; Feraheme – AMAG), an intravenous (IV) iron replacement product, has been approved by the FDA for treatment of iron deficiency anemia in adults with chronic kidney disease. Iron deficiency anemia is common in chronic kidney disease and may be associated with decreased absorption from the gastrointestinal tract, limiting the usefulness of oral iron replacement. IV iron replacement can lower the dose requirement for erythropoiesis-stimulating drugs, particularly in patients on dialysis
Drugs for Thyroid Disorders
The Medical Letter on Drugs and Therapeutics • August 1, 2009; (Issue 84)
Primary hypothyroidism is usually the result of Hashimoto's thyroiditis, thyroidectomy for hyperthyroidism, goiter or cancer, or radioactive iodine therapy for...
Primary hypothyroidism is usually the result of Hashimoto's thyroiditis, thyroidectomy for hyperthyroidism, goiter or cancer, or radioactive iodine therapy for hyperthyroidism.
Ropinirole for Restless Legs Syndrome
The Medical Letter on Drugs and Therapeutics • August 1, 2005; (Issue 1214)
Ropinirole (Requip - GlaxoSmithKline), a dopamine agonist already available for treatment of Parkinson's disease, is now the first drug approved by the FDA for treatment of moderate to severe restless legs...
Ropinirole (Requip - GlaxoSmithKline), a dopamine agonist already available for treatment of Parkinson's disease, is now the first drug approved by the FDA for treatment of moderate to severe restless legs syndrome (RLS).
Generic drugs
The Medical Letter on Drugs and Therapeutics • October 14, 2002; (Issue 1141)
When patents expire on brand-name drugs and generic formulations become available, patients and managed care organizations may express a preference for the lower-cost generics. Are they equivalent to the...
When patents expire on brand-name drugs and generic formulations become available, patients and managed care organizations may express a preference for the lower-cost generics. Are they equivalent to the brand-name product?
Cefdinir--A New Oral Cephalosporin
The Medical Letter on Drugs and Therapeutics • August 28, 1998; (Issue 1034)
Cefdinir (Omnicef - Parke-Davis), a third-generation oral cephalosporin, has been approved by the FDA for treatment of acute sinusitis, otitis media, acute exacerbations of chronic bronchitis, pharyngitis,...
Cefdinir (Omnicef - Parke-Davis), a third-generation oral cephalosporin, has been approved by the FDA for treatment of acute sinusitis, otitis media, acute exacerbations of chronic bronchitis, pharyngitis, community-acquired pneumonia and skin infections. Other drugs available for these indications are reviewed in The Medical Letter Handbook of Antimicrobial Therapy, 1998.
Trovafloxacin
The Medical Letter on Drugs and Therapeutics • March 13, 1998; (Issue 1022)
Trovafloxacin (Trovan - Pfizer) and its prodrug alatrofoxacin (Trovan IV) are new fluroroquinolones marketed for an unusually wide variety of infections, including oral and intravenous treatment of nosocomial...
Trovafloxacin (Trovan - Pfizer) and its prodrug alatrofoxacin (Trovan IV) are new fluroroquinolones marketed for an unusually wide variety of infections, including oral and intravenous treatment of nosocomial and community-acquired pneumonia, acute ecerbations of chronic bronchitis, acute sinusitis, complicate intra-abdominal and pelvic infections, diabetic foot infection, uncomplicated urinary tract infection, prostatitis, cervicitis and uncomplicated gonorrhea.
Grepafloxacin--A New Fluoroquinolone
The Medical Letter on Drugs and Therapeutics • January 30, 1998; (Issue 1019)
Grepafloxacin (Raxar - Glaxo Wellcome), a once-daily oral fluoroquinolone, is now being marketed for treatment of community-acquired pneumonia, acute bacterial exacerbations of chronic bronchitis, uncomplicated...
Grepafloxacin (Raxar - Glaxo Wellcome), a once-daily oral fluoroquinolone, is now being marketed for treatment of community-acquired pneumonia, acute bacterial exacerbations of chronic bronchitis, uncomplicated gonorrhea, and nongonococcal urethritis and cervicitis.