Penmenvy — A Second Pentavalent Meningococcal Vaccine
April 14, 2025 (Issue: 1726)
The FDA has licensed the pentavalent vaccine
Penmenvy (GSK) for prevention of invasive
meningococcal disease caused by Neisseria
meningitidis serogroups A, B, C, W, or Y (MenABCWY)
in persons 10-25 years old. Penmenvy is the second
pentavalent...more
- Penbraya: a pentavalent meningococcal vaccine. Med Lett Drugs Ther 2024; 66:43.
- CDC. Meningococcal disease surveillance and trends. November 12, 2024. Available at: https://bit.ly/4kN7eVC. Accessed March 27, 2025.
- T Nolan et al. Breadth of immune response, immunogenicity, reactogenicity, and safety for a pentavalent meningococcal ABCWY vaccine in healthy adolescents and young adults: results from a phase 3, randomised, controlled observer-blinded trial. Lancet Infect Dis 2024 December 5 (epub). doi:10.1016/s1473-3099(24)00667-4
- T Nolan et al. Immunogenicity, reactogenicity, and safety of a pentavalent meningococcal ABCWY vaccine in adolescents and young adults who had previously received a meningococcal ACWY vaccine: a phase 3, randomized controlled clinical study. Clin Infect Dis 2024 December 26 (epub). doi:10.1093/cid/ciae622
- JP Collins et al. Use of the Pfizer pentavalent meningococcal vaccine among persons aged ≥10 years: recommendations of the advisory committee on immunization practices ― United States, 2023. MMWR Morb Mortal Wkly Rep 2024; 73:345. doi:10.15585/mmwr.mm7315a4
- Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006-. Meningococcal vaccines. [Updated 2024 Aug 15]. Available at: https://bit.ly/41Z4kWq. Accessed March 27, 2025.
- SA Mbaeyi et al. Meningococcal vaccination: recommendations of the Advisory Committee on Immunization Practices, United States, 2020. MMWR Recomm Rep 2020; 69:1. doi:10.15585/mmwr.rr6909a1
- S Schillie et al. New dosing interval and schedule for the Bexsero MenB-4C vaccine: updated recommendations of the Advisory Committee on Immunization Practices — United States, October 2024. MMWR Morb Mortal Wkly Rep 2024; 73:1124. doi:10.15585/mmwr.mm7349a3
- CDC Advisory Committee on Immunization Practices. ACIP meeting information. March 24, 2025. Available at: https://bit.ly/3R2ICdN. Accessed March 27, 2025.
The Medical Letter is a subscriber-funded nonprofit organization that publishes critical appraisals of new prescription drugs and comparative reviews of drugs for common diseases.
Would you like to read the rest of this issue? Gain access below.
Subscribe
Subscriptions to
The Medical Letter on Drugs and Therapeutics include:
- Print version published and mailed biweekly (26 issues/year)
- Unlimited online access to current and past issues (1988 - present)
- Mobile App
- FREE online per issue CME/CE
Gain access through your organization
Ask your librarian to consider an Institutional Subscription to The Medical Letter.
